The development of new pathways by which organic molecules can be stereoselectively constructed remains an important direction for organic chemistry. The palladium-mediated cyclizations of Trost,' Stille? Hegedus,3 Larock," Negishi: and Overman6 and the radical cyclization reactions of Keck,' Stork: Hart: Curran,Io Barton," and Beckwith12 represent important new strategies. A comparatively unstudied strategy is the formation of bicyclic or tricyclic systems via reactive bridgehead intermediates.
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