One-Pot Synthesis of 2-Substituted Indoles from 2-Aminobenzyl Phosphonium Salts. A Formal Total Synthesis of Arcyriacyanin AOrganic Letters
Publication VersionPublished Version
AbstractThe reaction of (2-aminobenzyl) triphenylphosphonium bromide with aromatic aldehydes or α,β-unsaturated aldehydes under microwave-assisted conditions constitutes a new synthesis of 2-substituted indoles in high yields (81−97%) in a one-pot reaction. The adduct from indole-4-carboxaldehyde was an advanced intermediate in the synthesis of arcyriacyanin A.
Copyright OwnerAmerican Chemical Society
Citation InformationGeorge A. Kraus and Haitao Guo. "One-Pot Synthesis of 2-Substituted Indoles from 2-Aminobenzyl Phosphonium Salts. A Formal Total Synthesis of Arcyriacyanin A" Organic Letters Vol. 10 Iss. 14 (2008) p. 3061 - 3063
Available at: http://works.bepress.com/george_kraus/76/