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Article
Excited-State Photophysics of Hypericin and Its Hexamethoxy Analog:  Intramolecular Proton Transfer as a Nonradiative Process in Hypericin
Journal of American Chemical Society
  • D. S. English, Iowa State University
  • W. Zhang, Iowa State University
  • George A. Kraus, Iowa State University
  • Jacob W. Petrich, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
4-2-1997
DOI
10.1021/ja962476h
Abstract
The excited-state photophysics of the light induced antiviral agent, hypericin, are compared with those of its methylated analog, hexamethoxyhypericin. This comparison is instructive in understanding both the ground- and the excited-state properties of hypericin. That the hexamethoxy analog has no labile protons that can be transferred, that it cannot protonate its own carbonyl groups, that it has a reduced fluorescence quantum yield and lifetime with respect to hypericin, and that it exhibits no stimulated emission or, more specifically, rise time in stimulated emission completely support our emerging model of the hypericin photophysics. The results are consistent with the presence of intramolecular excited-state proton transfer in hypericin but not in its methylated analog.
Comments

Reprinted (adapted) with permission from Journal of American Chemical Society, 119(13); 2980-2986. Doi: 10.1021/ja962476h. Copyright 1997 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
D. S. English, W. Zhang, George A. Kraus and Jacob W. Petrich. "Excited-State Photophysics of Hypericin and Its Hexamethoxy Analog:  Intramolecular Proton Transfer as a Nonradiative Process in Hypericin" Journal of American Chemical Society Vol. 119 Iss. 13 (1997) p. 2980 - 2986
Available at: http://works.bepress.com/george_kraus/60/