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Article
Direct Synthesis of Chrysosplenol D
Journal of Natural Products
  • George A. Kraus, Iowa State University
  • Sudipta Roy, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
10-15-2008
DOI
10.1021/np800423j
Abstract

An aldol condensation and an Algar−Flynn−Oyamada oxidative cyclization were key steps in the direct synthesis of chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.

Comments

Reprinted (adapted) with permission from Journal of Natural Products, 71(11); 1961-1962. Doi: 10.1021/np800423j. Copyright 2008 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
George A. Kraus and Sudipta Roy. "Direct Synthesis of Chrysosplenol D" Journal of Natural Products Vol. 71 Iss. 11 (2008) p. 1961 - 1962
Available at: http://works.bepress.com/george_kraus/49/