A direct synthesis of racemic demethoxyaflatoxin B2The Journal of Organic Chemistry
Publication VersionPublished Version
AbstractAflatoxin analogue 19 was prepared by a direct sequence involving a novel silver-mediated cyclization to 12, the Michael addition of 16 with 17, and the oxidation of the Michael addition adduct. The overall yield of this six-step route is approximately 11%. The pathway is a flexible one that will permit the synthesis of analogues for toxicological analysis.
Copyright OwnerAmerican Chemical Society
Citation InformationGeorge A. Kraus, Beth E. Johnston and Jacqueline M. Applegate. "A direct synthesis of racemic demethoxyaflatoxin B2" The Journal of Organic Chemistry Vol. 56 Iss. 19 (1991) p. 5688 - 5691
Available at: http://works.bepress.com/george_kraus/24/