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Article
A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation
Tetrahedron Letters
  • George A. Kraus, Iowa State University
  • Pengfei Dong, Iowa State University
  • Yang Qu, Iowa State University
  • Alyssa Evans, Iowa State University
  • Susan Carpenter, Iowa State University
Document Type
Article
Publication Version
Accepted Manuscript
Publication Date
11-23-2016
DOI
10.1016/j.tetlet.2016.10.014
Abstract

A direct synthesis of atractylodinol from 2-furylbutenyne and bromoacetylene 6 is reported. Both compounds 1 and 8 showed greater than 99% virus inhibition.

Comments

This is a manuscript of an article published as Kraus, George A., Pengfei Dong, Yang Qu, Alyssa Evans, and Susan Carpenter. "A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation." Tetrahedron Letters 57, no. 47 (2016): 5185-5187. DOI: 10.1016/j.tetlet.2016.10.014. Posted with permission.

Creative Commons License
Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International
Copyright Owner
Elsevier Ltd.
Language
en
File Format
application/pdf
Citation Information
George A. Kraus, Pengfei Dong, Yang Qu, Alyssa Evans, et al.. "A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation" Tetrahedron Letters Vol. 57 Iss. 47 (2016) p. 5185 - 5187
Available at: http://works.bepress.com/george_kraus/236/