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Article
Triacetic acid lactone as a common intermediate for the synthesis of 4-hydroxy-2-pyridones and 4-amino-2-pyrones
Tetrahedron Letters
  • George A. Kraus, Iowa State University
  • Umayangani Wanninayake, Iowa State University
  • Jashaun Bottoms, Iowa State University
Document Type
Article
Disciplines
Publication Version
Accepted Manuscript
Publication Date
12-1-2015
DOI
10.1016/j.tetlet.2016.02.043
Abstract

At ambient temperature, triacetic acid lactone reacts with amines to produce 4-amino-2-pyrones. If the temperature is raised to 100 °C, 4-hydroxy-2-pyridones are generated.

Comments

This is a manuscript of an article published as Kraus, George A., Umayangani K. Wanninayake, and Jashaun Bottoms. "Triacetic acid lactone as a common intermediate for the synthesis of 4-hydroxy-2-pyridones and 4-amino-2-pyrones." Tetrahedron Letters 57, no. 11 (2016): 1293-1295. 10.1016/j.tetlet.2016.02.043. Posted with permission.

Creative Commons License
Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International
Copyright Owner
Elsevier Ltd.
Language
en
File Format
en
File Size
application/pdf
Citation Information
George A. Kraus, Umayangani Wanninayake and Jashaun Bottoms. "Triacetic acid lactone as a common intermediate for the synthesis of 4-hydroxy-2-pyridones and 4-amino-2-pyrones" Tetrahedron Letters Vol. 57 Iss. 11 (2015) p. 1293 - 1295
Available at: http://works.bepress.com/george_kraus/228/