Synthesis of deoxyfrenolicin and nanaomycin AThe Journal of Organic Chemistry
Publication VersionPublished Version
AbstractDeoxyfrenolicin and nanaomycin A have been synthesized. Key steps in the synthesis include a phthalide annulation reaction to produce a naphthoquinone, a tandem Diels-Alder/retro-Claisen reaction to produce the carbon skeleton, and a stereoselective reduction of a hemiketal.
Copyright OwnerAmerican Chemical Society
Citation InformationGeorge A. Kraus, Maria T. Molina and John A. Walling. "Synthesis of deoxyfrenolicin and nanaomycin A" The Journal of Organic Chemistry Vol. 52 Iss. 7 (1987) p. 1273 - 1276
Available at: http://works.bepress.com/george_kraus/197/