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Article
Synthesis of deoxyfrenolicin and nanaomycin A
The Journal of Organic Chemistry
  • George A. Kraus, Iowa State University
  • Maria T. Molina, Iowa State University
  • John A. Walling, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
4-1-1987
DOI
10.1021/jo00383a018
Abstract
Deoxyfrenolicin and nanaomycin A have been synthesized. Key steps in the synthesis include a phthalide annulation reaction to produce a naphthoquinone, a tandem Diels-Alder/retro-Claisen reaction to produce the carbon skeleton, and a stereoselective reduction of a hemiketal.
Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 52(7); 1273-1276. Doi: 10.1021/jo00383a018. Copyright 1987 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
George A. Kraus, Maria T. Molina and John A. Walling. "Synthesis of deoxyfrenolicin and nanaomycin A" The Journal of Organic Chemistry Vol. 52 Iss. 7 (1987) p. 1273 - 1276
Available at: http://works.bepress.com/george_kraus/197/