Stereoselective synthesis of calonectrinJournal of The American Chemical Society
Publication VersionPublished Version
AbstractSeveral macrocyclic lactones of the trichothecene class of compounds exhibit significant anticancer activity.' A common structural subunit in each of these lactones is the sesquiterpene verrucarol(1). Anguidin (2), a more highly oxygenated analogue, also shows inhibitory activity against several cancers., Calonectrin (3), considered to be the biogenetic precursor to verru~arol,~ has recently been isolated.
Copyright OwnerAmerican Chemical Society
Citation InformationGeorge A. Kraus, Bruce Roth, Kevin Frazier and Masayuki Shimagaki. "Stereoselective synthesis of calonectrin" Journal of The American Chemical Society Vol. 104 Iss. 4 (1982) p. 1114 - 1116
Available at: http://works.bepress.com/george_kraus/179/