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Article
Hydrogen atom abstraction reactions in organic synthesis. A formal total synthesis of racemic podophyllotoxin
The Journal of Organic Chemistry
  • George A. Kraus, Iowa State University
  • Yusheng Wu, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
5-1-1992
DOI
10.1021/jo00036a030
Abstract

The key step in a synthesis of 1 was a tandem photoenolization/Diels-Alder reaction to produce 11. Hydrolysis of the acetal and ester followed by oxidation afforded 15, an advanced intermediate in the Meyers synthesis of 1.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 57(10); 2922-2925. Doi: 10.1021/jo00036a030. Copyright 1992 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
George A. Kraus and Yusheng Wu. "Hydrogen atom abstraction reactions in organic synthesis. A formal total synthesis of racemic podophyllotoxin" The Journal of Organic Chemistry Vol. 57 Iss. 10 (1992) p. 2922 - 2925
Available at: http://works.bepress.com/george_kraus/149/