Skip to main content
Article
Synthesis of a precursor to quassimarin
The Journal of Organic Chemistry
  • George A. Kraus, Iowa State University
  • Michael E. Krolski, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
8-1-1986
DOI
10.1021/jo00367a017
Abstract

An intermediate containing the ACE ring system of quassimarin was prepared. The isopropylidene malonate 8 reacted with diene 2 to afford two Diels-Alder adducts. The major adduct was converted into lactone 11 by a sequence involving epoxidation followed by acid-mediated epoxide opening and lactonization.

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 51(17); 3347-3350. Doi: 10.1021/jo00367a017. Copyright 1986 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
George A. Kraus and Michael E. Krolski. "Synthesis of a precursor to quassimarin" The Journal of Organic Chemistry Vol. 51 Iss. 17 (1986) p. 3347 - 3350
Available at: http://works.bepress.com/george_kraus/106/