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Quantification of Mitral Regurgitation With MR Phase-Velocity Mapping Using a Control Volume Method
Journal of Magnetic Resonance Imaging
  • George P Chatzimavroudis, Cleveland State University
  • John N. Oshinski, Emory University Hospital
  • Roderic I. Pettigrew, Emory University Hospital
  • Peter G. Walker, University of Leeds
  • Robert H. Franch, Emory University Hospital
  • Ajit P. Yoganathan, Georgia Institute of Technology
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Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of which excluded the region of flow acceleration and aliasing at the orifice, provided accurate measurements of the regurgitant flow. A smaller CV provided erroneous results because of flow acceleration and velocity aliasing close to the orifice. A large CV generally provided inaccurate results because of reduced velocity sensitivity far from the orifice. Aortic outflow, orifice shape, and valve geometry did not affect the accuracy of the CV measurements. The CV method is a promising approach to the problem of quantification of the MRV.

This work was supported by a grant from the American Heart Association-Georgia Affiliate. This work was presented at the 5th annual scientific meeting of the International Society for Magnetic Resonance in Medicine. Vancouver. 1997.

Citation Information
Chatzimavroudis GP, Oshinski JN, Pettigrew RI, Walker PG, Franch RH, Yoganathan AP. Quantification of mitral regurgitation with MR phase-velocity mapping using a control volume method. Journal of Magnetic Resonance Imaging. 1998;8:577-582.