Article
Identifying Antigens and Antibodies in Serology
Mathematical Biosciences
Abstract
The problem of whether it is theoretically possible to determine antigens and antibodies in a cross-reacting serological system is analyzed. Conditions are listed which will insure that the serological operations of absorption, elution, blocking, and counterblocking uniquely determine antigens and antibodies. There is no restriction on cross-reactivity. The protocol for counterblocking was given by Denniston and has not been developed by serologists. Denniston has shown that counterblocking can be replaced by combinations ofthe other operations in a system where there can be no cross-reactivity. This paper indicates the potential usefulness of such a technique.
Department(s)
Computer Science
Keywords and Phrases
- Immunology,
- Antibody,
- Antigen,
- Nonbiological Model,
- Nonhuman
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 1983 Elsevier, All rights reserved.
Publication Date
10-1-1983
Publication Date
01 Oct 1983
Disciplines
Citation Information
George Markowsky and Andrew Wohlgemuth. "Identifying Antigens and Antibodies in Serology" Mathematical Biosciences Vol. 66 Iss. 2 (1983) p. 273 - 282 ISSN: 0025-5564 Available at: http://works.bepress.com/george-markowsky/37/