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Type I, bovine skin collagen was allowed to gel in the presence of various concentrations of a carbon nanotube material covered with a polystyrene/polyaniline copolymer, called a carbon nanobrush (CNB). The rate of collagen gelation was enhanced by the presence of the CNB in a dose dependent manner. The extent of collagen gelation was due to the concentration of collagen and not the amount of CNB. Collagen D-periodicity, and average fibril diameter were unchanged by the CNB material as seen in transmission electron micrographs. Gel tensile strength was reduced by the presence of the CNB in a dose related manner. The collagen-CNB mixture may have a role in the repair and reconstruction of wounds or degenerated connective tissue.
Dombi, G.W., Purohit, K., Martin, L.M. et al. J Mater Sci: Mater Med (2015) 26: 30. https://doi.org/10.1007/s10856-014-5356-4
Available at: http://dx.doi.org/10.1007/s10856-014-5356-4
George W. Dombi, Kaushalkumar Purohit and Sze C. Yang are from the Department of Chemistry.
Lenore M. Martin is from the Department of Cell and Molecular Biology.