Colorectal cancer is the second most common cancer for males and females combined, after lung cancer. A diet rich in fruits and vegetables may play a role in colorectal cancer prevention. During March 13-18, 2009, the Colorectal Cancer Awareness Network (CRAN) of Southeastern Michigan, in partnership with Get Your Guts in Gear presented CoCo the Colossal Colon®, a 40-foot long, human colon model at the Detroit Science Center. Healthyfood card matching games were played to reinforced the message of fruit and vegetable consumption for good colon health. The goal of this report is to show how to make and use card matching games at a Public Health event.