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Article
Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris
Current Opinion in Biotechnology
  • Geoff P. Lin-Cereghino, University of the Pacific
  • Joan Lin-Cereghino, University of the Pacific
  • Christine Ilgen, Keck Graduate Institute of Applied Life Sciences
  • James Cregg, Keck Graduate Institute of Applied Life Sciences
Document Type
Article
Department
Biological Sciences
DOI
10.1016/S0958-1669(02)00330-0
Publication Date
8-1-2002
Abstract

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

Citation Information
Geoff P. Lin-Cereghino, Joan Lin-Cereghino, Christine Ilgen and James Cregg. "Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris" Current Opinion in Biotechnology Vol. 13 Iss. 4 (2002) p. 329 - 332 ISSN: 0958-1669
Available at: http://works.bepress.com/geoff-lin-cereghino/28/