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About Genevieve Eastabrook

Dr. Genevieve Eastabrook is an obstetrician at the Children's Hospital (LHSC) and an assistant professor in the Department of Obstetrics and Gynecology, Western University, as well as director of the school's Maternal Fetal Medicine Subspecialty Training Program.

Asset Map Keywords: IUGR, MRI Technology, and Preeclampsia --> (see more)
Children's Health Collaborators: Barbra De Vrijer, Stephen J Renaud, and Debbie Penava


Dr. Eastabrook completed medical school at the University of Calgary before embarking on her OBGYN residency training program at the University of British Columbia (UBC). Following this, she completed a fellowship in Maternal Fetal Medicine, as well as the Royal College certified Clinical Investigator Program, also at UBC. Her research focus at that time was on role of the maternal immune system in both normal and pathologic placentation, as well as on the role of the placenta in preeclampsia. In 2012, she joined Western’s division of Maternal Fetal Medicine as a clinician-researcher. In May 2017, she took on the role of director of the MFM subspecialty training program.

Research
As a member of the Pregnancy Research Group, Dr. Eastabrook’s current research focus is on placental dysfunction and cardiovascular maladaptation to pregnancy, particularly within the obese population.

With the Pregnancy Research Group, Dr. Eastabrook conducts clinical research focusing on better identification of maternal risk factors associated with adverse pregnancy outcome, detection of abnormal fetal metabolism and placental function, with the goal to improve pregnancy outcome and long term consequences of abnormal intrauterine environment such as childhood obesity and diabetes. Some examples of the Pregnancy Research Group’s research include:

  • Development and application of novel MRI-based technologies to contribute to our understanding and ability to detect abnormal metabolism inside the womb
  • Assessment of maternal cardiovascular health and determination of its clinical utility for pregnancies in women with high BMI, using Pulse Wave Velocity
  • Investigation of changes in metabolic and inflammatory markers, decorin levels and placental autophagy in patients with obesity and/or preeclampsia
  • Investigation of the effect of maternal obesity, mode of delivery and preventative use of antibiotics for Group B streptococci on the early development of the infant’s microbiota
  • Assessment of women’s and clinicians’ experiences with pregnancy care for women with obesity, participation in clinical research, prenatal testing and future health of the baby

Funding
Dr. Eastabrook, together with Co-Principal Investigator Dr. Barbra de Vrijer and co-investigators Drs. Han, Lala, McKenzie, Penava, Regnault, Shepherd and Siu, hold a CIHR/SOGC MFM Team grant.  Drs. Eastabrook and Lala also currently hold a CHRI Translational Research Grant.

Positions

Present Assistant Professor, Western University Department of Obstetrics and Gynaecology
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Present Director of Maternal Fetal Medicine Subspecialty Training Program, Western University Schulich School of Medicine & Dentistry
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Present OBGYN-MFM, London Health Sciences Centre ‐ Children's Hospital
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Present Scientist, Lawson Health Research Institute ‐ Children's Health Research Institute (CHRI)
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