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A chicken genomic DNA fragment that hybridizes to the murine Hox-3.1 homeobox is likely to encode the NADH ubiquinone oxidoreductase subunit B15
Gene (1993)
  • Gary Goldberg, Rowan University School of Osteopathic Medicine
  • Walter Kaczmarczyk
Abstract
A chicken DNA fragment, which was isolated from a cosmid genomic library using a murine homeobox probe, is shown here to be a likely candidate for encoding a protein homologous to the bovine B15 subunit of NADH ubiquinone oxidoreductase. The genomic sequence suggests the presence of an intron separating two coding regions. An alignment between the bovine NADH B15 protein and its putative avian homolog implies the presence of conserved domains, including a transmembrane helix, tyrosine sulfatation site, and a phosphorylation consensus site.
Keywords
  • Homology,
  • cloning,
  • sequence,
  • open reading frame,
  • gene
Disciplines
Publication Date
November 15, 1993
DOI
10.1016/0378-1119(93)90644-I
Citation Information
Gary Goldberg and Walter Kaczmarczyk. "A chicken genomic DNA fragment that hybridizes to the murine Hox-3.1 homeobox is likely to encode the NADH ubiquinone oxidoreductase subunit B15" Gene Vol. 133 Iss. 2 (1993) p. 233 - 235 ISSN: 0378-1119
Available at: http://works.bepress.com/gary-s-goldberg/47/