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Selected Works of Gary S. Goldberg
Article
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression
Carcinogenesis (2015)
  • Rita Nahta, Emory University
  • Fahd Al-Mulla, Kuwait University
  • Rabeah Al-Temaimi, Kuwait University
  • Amedeo Amedei, University of Florence
  • Rafaela Andrade-Vieira, Dalhousie University
  • Sarah N. Bay, Emory University
  • Dustin G. Brown, Colorado School of Public Health
  • Gloria M. Calaf, University of Tarapacá
  • Gloria M. Calaf, Columbia University Medical Center
  • Robert C. Castellino, Emory University
  • Karine A. Cohen-Solal, Cancer Institute
  • Anna Maria Colacci, 10 Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna 40126, Italy,
  • Nichola Cruickshanks, Virginia Commonwealth University
  • Paul Dent, Virginia Commonwealth University
  • Riccardo Di Fiore, University of Palermo
  • Stefano Forte, 13 Mediterranean Institute of Oncology, 95029 Viagrande, Italy,
  • Gary S. Goldberg, Rowan University School of Osteopathic Medicine
  • Roslida A. Hamid, 15 Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra, Serdang, Selangor 43400, Malaysia,
  • Harini Krishnan, Rowan University School of Osteopathic Medicine
  • Dale W. Laird, University of Western Ontario
  • Ahmed Lasfar, Rutgers University
  • Paola A. Marignani, Dalhousie University
  • Lorenzo Memeo, 13 Mediterranean Institute of Oncology, 95029 Viagrande, Italy,
  • Chiara Mondello, National Research Council
  • Christian C. Naus, University of British Columbia
  • Richard Ponce-Cusi, University of Tarapacá
  • Jayadev Raju, Health Canada
  • Debasish Roy, City University of New York
  • Rabindra Roy, Georgetown University Medical Center
  • Elizabeth P. Ryan, Colorado School of Public Health
  • Hosni K. Salem, Cairo University
  • A.Ivana Scovassi, National Research Council
  • Neetu Singh, King George's Medical University
  • Monica Vaccari, 10 Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna 40126, Italy,
  • Renza Vento, College of Science and Technology
  • Renza Vento, University of Palermo
  • Jan Vondráček, 26 Department of Cytokinetics, Institute of Biophysics AS CR, Brno 612 65, Czech Republic,
  • Mark Wade, Istituto Italiano di Tecnologia
  • Jordan Woodrick, Georgetown University Medical Center
  • William H. Bisson, Oregon State University
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Abstract
As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
Keywords
  • Environmental Exposure,
  • Hazardous Substances,
  • Neoplasms,
  • Signal Transduction
Disciplines
Publication Date
January 6, 2015
DOI
10.1093/carcin/bgv028
Citation Information
Rita Nahta, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, et al.. "Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression" Carcinogenesis Vol. 36 Iss. Suppl. 1 (2015) p. S2 - S18 ISSN: Online: 1460-2180; Print: 0143-3334
Available at: http://works.bepress.com/gary-s-goldberg/34/