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Article
Bioprosthetic Aortic Valve Durability: A Meta-Regression of Published Studies.
The Annals of thoracic surgery
  • M Wang, Medical Data Research Center, Providence Health and Services, Portland, OR, USA
  • Anthony P Furnary
  • Hsin-Fang Li, Providence St Vincent Medical Center
  • Gary Grunkemeier, Medical Data Research Center, Providence Health and Services, Portland, Oregon
Document Type
Article
Publication Date
9-1-2017
Keywords
  • Animals,
  • Aortic Valve,
  • Bioprosthesis,
  • Heart Valve Diseases,
  • Heart Valve Prosthesis,
  • Humans,
  • Prosthesis Design,
  • cards
Disciplines
Abstract

To compare structural valve deterioration (SVD) among bioprosthetic aortic valve types, a PubMed search found 54 papers containing SVD-free curves extending to at least 10 years. The curves were digitized and fit to Weibull distributions, and the mean times to valve failure (MTTF) were calculated. Twelve valve models were collapsed into four valve types: Medtronic (Medtronic, Minneapolis, MN) and Edwards (Edwards Lifesciences, Irvine, CA) porcine; and Sorin (Sorin Group [now LivaNova], London, United Kingdom) and Edwards pericardial. Meta-regression found MTTF was associated with the patient's age, publication year, SVD definition, and valve type. Sorin pericardial valves had significantly lower risk-adjusted MTTF (higher SVD risk), and there were no significant differences in MTTF among the other three valve types.

Clinical Institute
Cardiovascular (Heart)
Specialty
Cardiology
Specialty
Center for Cardiovascular Analytics, Research + Data Science (CARDS)
Citation Information
M Wang, Anthony P Furnary, Hsin-Fang Li and Gary Grunkemeier. "Bioprosthetic Aortic Valve Durability: A Meta-Regression of Published Studies." The Annals of thoracic surgery (2017)
Available at: http://works.bepress.com/gary-grunkemeier/239/