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Article
Extraskeletal Effects of Vitamin D: Potential Impact on WV Disease Morbidity and Mortality
Orthopaedics
  • Franklin D. Shuler, Marshall University
  • Dana Lycans
  • Elias Salloum
Document Type
Article
Publication Date
1-1-2012
Abstract
Vitamin D is an essential nutrient and a secosteroid hormone that regulates many physiologic processes beyond calcium and bone homeostasis. These "extraskeletal" effects are impacted by the circulating levels of the storage form of vitamin D, 25-hydroxyvitamin D3. Levels of vitamin D can be detected after completing a simple 25(OH)D blood test. Vitamin D deficiency (< 30 ng/mL) is associated with a higher risk of many chronic diseases including, but not limited to, fourteen types of cancers, type 1 and 2 diabetes mellitus, obesity, cardiovascular disease, hypertension, stroke, and asthma. This article explores the association between vitamin D deficiency and the burden of chronic diseases in West Virginia.
Comments

CME issue on the Art, Science and Ethics of Prevention. WV Medical Journal. The copy of record is available from the publisher at http://www.wvsma.com/Portals/0/MayJune2012.pdf. Copyright © 2012 West Virginia State Journal of Medicine. Reprinted with permission. All rights reserved.

Citation Information
Shuler FD, Lycans D, Salloum E. Extraskeletal effects of Vitamin D: Potential impact on WV disease morbidity and mortality. W V Med J. 2012; 108(3):56-62.