The hypothetical protein PF0899 is a 95-residue peptide from the hyperthermophilic archaeon Pyrococcus furiosus that represents a gene family with six members. P. furiosus ORF PF0899 has been cloned, expressed and crystallized and its structure has been determined by the Southeast Collaboratory for Structural Genomics (http://www.secsg.org). The structure was solved using the SCA2Structure pipeline from multiple data sets and has been refined to 1.85 A against the highest resolution data set collected (a presumed gold derivative), with a crystallographic R factor of 21.0% and R(free) of 24.0%. The refined structure shows some structural similarity to a wedge-shaped domain observed in the structure of the major capsid protein from bacteriophage HK97, suggesting that PF0899 may be a structural protein.
Available at: http://works.bepress.com/francis_jenney/75/
This article was published in Acta Crystallographica Section F, Structural Biology and Crystallization Communications. Volume 63, Pt 7, July 2007, Pages 549-552.
The published version is available at http://dx.doi.org/10.1107/S1744309107024049
Copyright © 2007 International Union of Crystallography