Pharmacologist; Division Head, Clinical Pharmacology; Associate Professor
Dr. Facundo Garcia-Bournissen is a pharmacologist specializing in improving medicine use in children by simplifying complex medical treatments, helping prevent or manage adverse drug reactions, and evaluating medication failures.
Asset Map Keywords: Drug Development, Infectious Diseases and Disorders, Pediatric Early Phase Studies, Population Pharmacokinetics and Pharmacodynamics, Drugs in Pregnancy and Lactation, and Neglected Diseases --> (see more)
Children's Health Collaborators: Michael Rieder, Janine Hutson, Barbra DeVrijer, Erkan Demirkaya, Craig Campbell, Brad Urquhart, Eileen Crowley
Dr. Garcia-Bournissen's often-collaborative, clinical and laboratory-based research is centered around medications for children and pregnant women, and involves studying the mechanisms behind drug resistance and drug-averse events in children, as well as how to improve the use of pediatric medications so that they are more effective and less toxic.
He is particularly interested in developing medications for neglected and for rare diseases, that is, diseases that affect few children or for which there are currently no good treatments available, especially for children in underserviced populations. This includes studying new medications but also old ones that may have potential for being used in new diseases. Dr Garcia-Bournissen also studies the risks and benefits of using medications during pregnancy and breastfeeding, using epidemiological research and translational research in collaboration with Maternal Fetal Medicine clinical researchers.
Finally, Dr Garcia-Bournissen is interested in applying statistical and pharmacological research methods (such as population pharmacokinetics and pharmacodynamics modelling, mass spectrometry methods for drug and metabolite analysis, and other methods) to better design and analyze pediatric drug studies and help improve pediatric medication use.
Dr Facundo Garcia-Bournissen is a pediatrician, clinician scientist and clinical pharmacologist trained in Argentina and Canada. He obtained his MD and pediatric specialty degree from the University of Buenos Aires (Argentina), followed by post-graduate training at Hôpital Ste. Justine in Montreal, and, later did his PhD, clinical pharmacology fellowship and clinician scientist training at The Hospital for Sick Children in Toronto (Canada).
After training in Canada, he returned to Argentina to work as Independent Researcher at the Buenos Aires Children’s Hospital doing translational research on the pharmacology of medications for pediatric neglected diseases. He actively participated in the design and implementation of pediatric clinical trials (e.g. prospective population pharmacokinetics studies and randomized clinical trials), and basic research (e.g. in vivo and in vitro studies to study drug metabolism, and drug activity for repositioning for treatment of neglected diseases). He also designed and participated in paediatric clinical trials that supported registration of drugs for Chagas disease in several countries.
Dr Facundo Garcia-Bournissen is a member of the American Board of Clinical Pharmacology, acting chair of the International Union of Pharmacology (IUPHAR) Section of Pediatric Clinical Pharmacology, and is actively participates in several scientific societies and international collaborations focused on developing medications for underserviced populations suffering from neglected diseases.
His current research efforts are mainly focused on studying the clinical pharmacology of medications in pediatrics, pregnancy and lactation, and translational research on medications for pediatric diseases, in particular those for neglected and vulnerable populations. He is especially interested in the mechanisms behind drug resistance, and drug adverse events, and in the interaction between genetics, growth, medications and pediatric disease.
Dr Facundo Garcia-Bournissen is a pediatrician, clinician scientist and clinical pharmacologist currently working as Head of the Division of Pediatric Clinical Pharmacology, Department of Pediatrics, London Health Sciences Centre, London Ontario Canada. He obtained his MD and pediatric specialty degree from the University of Buenos Aires, followed by post-graduate training at Hôpital Ste. Justine (Canada) and PhD, clinical pharmacology fellowship and clinician scientist training at University of Toronto (Canada). He is a member of the American Board of Clinical Pharmacology, vice-chair of the International Union of Pharmacology (IUPHAR) Section of Pediatric Clinical Pharmacology, and active member of several scientific societies. His current research is mainly focused on the clinical and basic pharmacology of medications for neglected diseases in children and vulnerable populations, including the design and implementation of clinical trials (e.g. prospective pediatric population pharmacokinetics studies), and basic research (e.g. in vivo and in vitro studies of drugs for repositioning for the treatment of Chagas disease) in these conditions. Dr Facundo Garcia-Bournissen is currenly Associate Professor of the Departments of Pediatrics, Medicine, Epidemiology & Biostatistics, and Pharmacology & Physiology, Schulich School of Medicine & Dentistry, University of Western Ontario
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About Facundo Garcia-Bournissen
Dr. Facundo Garcia-Bournissen is a pharmacologist specializing in improving medicine use in children by simplifying complex medical treatments, helping prevent or manage adverse drug reactions, and evaluating medication failures.
Asset Map Keywords: Drug Development, Infectious Diseases and Disorders, Pediatric Early Phase Studies, Population Pharmacokinetics and Pharmacodynamics, Drugs in Pregnancy and Lactation, and Neglected Diseases --> (see more)
Children's Health Collaborators: Michael Rieder, Janine Hutson, Barbra DeVrijer, Erkan Demirkaya, Craig Campbell, Brad Urquhart, Eileen Crowley
Dr. Garcia-Bournissen's often-collaborative, clinical and laboratory-based research is centered around medications for children and pregnant women, and involves studying the mechanisms behind drug resistance and drug-averse events in children, as well as how to improve the use of pediatric medications so that they are more effective and less toxic.
He is particularly interested in developing medications for neglected and for rare diseases, that is, diseases that affect few children or for which there are currently no good treatments available, especially for children in underserviced populations. This includes studying new medications but also old ones that may have potential for being used in new diseases. Dr Garcia-Bournissen also studies the risks and benefits of using medications during pregnancy and breastfeeding, using epidemiological research and translational research in collaboration with Maternal Fetal Medicine clinical researchers.
Finally, Dr Garcia-Bournissen is interested in applying statistical and pharmacological research methods (such as population pharmacokinetics and pharmacodynamics modelling, mass spectrometry methods for drug and metabolite analysis, and other methods) to better design and analyze pediatric drug studies and help improve pediatric medication use.
Dr Facundo Garcia-Bournissen is a pediatrician, clinician scientist and clinical pharmacologist trained in Argentina and Canada. He obtained his MD and pediatric specialty degree from the University of Buenos Aires (Argentina), followed by post-graduate training at Hôpital Ste. Justine in Montreal, and, later did his PhD, clinical pharmacology fellowship and clinician scientist training at The Hospital for Sick Children in Toronto (Canada).
After training in Canada, he returned to Argentina to work as Independent Researcher at the Buenos Aires Children’s Hospital doing translational research on the pharmacology of medications for pediatric neglected diseases. He actively participated in the design and implementation of pediatric clinical trials (e.g. prospective population pharmacokinetics studies and randomized clinical trials), and basic research (e.g. in vivo and in vitro studies to study drug metabolism, and drug activity for repositioning for treatment of neglected diseases). He also designed and participated in paediatric clinical trials that supported registration of drugs for Chagas disease in several countries.
Dr Facundo Garcia-Bournissen is a member of the American Board of Clinical Pharmacology, acting chair of the International Union of Pharmacology (IUPHAR) Section of Pediatric Clinical Pharmacology, and is actively participates in several scientific societies and international collaborations focused on developing medications for underserviced populations suffering from neglected diseases.
His current research efforts are mainly focused on studying the clinical pharmacology of medications in pediatrics, pregnancy and lactation, and translational research on medications for pediatric diseases, in particular those for neglected and vulnerable populations. He is especially interested in the mechanisms behind drug resistance, and drug adverse events, and in the interaction between genetics, growth, medications and pediatric disease.
Dr Facundo Garcia-Bournissen is a pediatrician, clinician scientist and clinical pharmacologist currently working as Head of the Division of Pediatric Clinical Pharmacology, Department of Pediatrics, London Health Sciences Centre, London Ontario Canada. He obtained his MD and pediatric specialty degree from the University of Buenos Aires, followed by post-graduate training at Hôpital Ste. Justine (Canada) and PhD, clinical pharmacology fellowship and clinician scientist training at University of Toronto (Canada). He is a member of the American Board of Clinical Pharmacology, vice-chair of the International Union of Pharmacology (IUPHAR) Section of Pediatric Clinical Pharmacology, and active member of several scientific societies. His current research is mainly focused on the clinical and basic pharmacology of medications for neglected diseases in children and vulnerable populations, including the design and implementation of clinical trials (e.g. prospective pediatric population pharmacokinetics studies), and basic research (e.g. in vivo and in vitro studies of drugs for repositioning for the treatment of Chagas disease) in these conditions. Dr Facundo Garcia-Bournissen is currenly Associate Professor of the Departments of Pediatrics, Medicine, Epidemiology & Biostatistics, and Pharmacology & Physiology, Schulich School of Medicine & Dentistry, University of Western Ontario
| Present | Associate Professor, Western University ‐ Department of Epidemiology and Biostatistics | |
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| Present | Associate Professor, Western University ‐ Department of Medicine | |
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| Present | Division Head, Clinical Pharmacology; Associate Professor, Western University ‐ Department of Paediatrics | |
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| Present | Pharmacologist, London Health Sciences Centre ‐ Children's Hospital | |
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Disciplines
Research Interests
Drug Development, Infectious Diseases and Disorders, Neglected Diseases, Clinical Trials, Global Health, Vulnerable Populations, Drug Response, Drug Metabolism, Rare Diseases and Disorders, Drug Repurposing, Pharmacokinetics/Pharmacodynamics, Clinical Research, Children's Health, Personalized Medicine, Adverse Drug Reactions, Drug Safety, Underserviced Populations, Pediatric Early Phase Studies, and Drugs in Pregnancy and Lactation