The purpose of this special issue is to help schools better understand how they might get started with implementing a strong Tier 2 system within the context of a multitiered service delivery model. The promise of multitiered service delivery models is that students who struggle can be identified early and receive interventions before their challenges become intractable. In this issue, a series of articles describe how one school implemented Tier 2 systems to address the needs of struggling students in reading, math, writing, and behavior. In addition, the systems that schools need to facilitate Tier 2 implementation are described.