Article
synder: inferring genomic orthologs from synteny maps
bioRxiv
Document Type
Article
Disciplines
Publication Version
Submitted Manuscript
Publication Date
2-19-2019
DOI
10.1101/554501
Abstract
Ortholog inference is a key step in understanding the evolution and function of a gene or other genomic feature. Yet often no similar sequence can be identified, or the true ortholog is hidden among false positives. A solution is to consider the sequence's genomic context. We present the generic program, synder, for tracing features of interest between genomes based on a synteny map. This approach narrows genomic search-space independently of the sequence of the feature of interest. We illustrate the utility of synder by finding orthologs for the Arabidopsis thaliana 13-member gene family of Nuclear Factor YC transcription factor across the Brassicaceae clade.
Creative Commons License
Creative Commons Attribution 4.0
Copyright Owner
Author/Funder
Copyright Date
2019
Language
en
File Format
application/pdf
Citation Information
Zebulun Arendsee, Andrew Wilkey, Urminder Singh, Jing Li, et al.. "synder: inferring genomic orthologs from synteny maps" bioRxiv (2019) Available at: http://works.bepress.com/eve-wurtele/68/
This is a pre-print made available through bioRxiv at doi: 10.1101/554501.