The amount of moisture which textile fibers are capable of absorbing affects their use in activewear. By making a functional analogy to natural systems via the biomimetic framework, the aim is to develop knitted fabrics that can change shape in response to changing environmental conditions, without any other control mechanisms or energy (Fratzl & Weinkamer, 2007). Few researchers have studied the responsive behavior for fibers and textiles, specifically natural fibers in a knitted fabric (Scott, 2015). This research documents the exploration of moisture responsiveness for forty different wool based fabrics, constructed via Santoni seamless knitting technology.