In the north-central region, a few persistent and many occasional insects occur in soybean. A potential mix of pests is likely to happen each growing season, but the severity is not easily predicted between years. Even though pest abundance can be erratic in Iowa soybean, there has been a steady adoption of insecticidal seed and foliar treatments over the last decade (Ragsdale et al. 2011). In order to preserve chemical efficacy and improve profit margins in soybean, we encourage farmers to use Integrated Pest Management, or IPM. The use of proactive IPM tools is an ideal way to manage a pest complex that often occurs in soybean. Examples of IPM for soybean aphid include genetic, cultural and chemical control; sampling; and knowledge of crop economics (Hodgson et al. 2012). Management of two important Iowa soybean pests, soybean aphid and twospotted spider mite, will be reviewed in this article.