PiRNA-like RNAs in the marsupial Monodelphis domestica identify transcription clusters and likely marsupial transposon targetsMammalian genome
NLM Title AbbreviationMamm Genome
DOI of Published Version10.1007/s00335-008-9109-x
AbstractPIWI-interacting RNAs (piRNAs) are a recently discovered class of small noncoding RNAs that have been detected in human, mouse, rat, zebrafish, and Drosophila genomes. We have utilized a size-directed small-RNA cloning procedure to clone and map more than 300 candidate piRNA-like small RNAs in the genome of the marsupial species Monodelphis domestica. Our results are consistent with those from other species in that the piRNA-like candidate sequences range in size from 28 to 31 nucleotides, show a pronounced preference for uridine at the 5' end, are transcribed from a few large clusters, appear to target transposons, and display virtually no sequence conservation.
- Base Sequence,
- Clone Cells,
- DNA Transposable Elements/genetics,
- Molecular Sequence Data,
- Multigene Family,
- Small Interfering/genetics,
Published Article/Book CitationMammalian genome, 19:7-8 (2008) pp.581-586.
Citation InformationEric J. Devor, L. Huang and P. B. Samollow. "PiRNA-like RNAs in the marsupial Monodelphis domestica identify transcription clusters and likely marsupial transposon targets" Mammalian genome Vol. 19 Iss. 7-8 (2008) p. 581 - 586 ISSN: 0938-8990
Available at: http://works.bepress.com/eric_devor/40/