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Article
PiRNA-like RNAs in the marsupial Monodelphis domestica identify transcription clusters and likely marsupial transposon targets
Mammalian genome
  • Eric J. Devor, University of Iowa
  • L. Huang
  • P. B. Samollow
Document Type
Article
Peer Reviewed
1
Publication Date
8-1-2008
NLM Title Abbreviation
Mamm Genome
PubMed ID
18473137
DOI of Published Version
10.1007/s00335-008-9109-x
Abstract

PIWI-interacting RNAs (piRNAs) are a recently discovered class of small noncoding RNAs that have been detected in human, mouse, rat, zebrafish, and Drosophila genomes. We have utilized a size-directed small-RNA cloning procedure to clone and map more than 300 candidate piRNA-like small RNAs in the genome of the marsupial species Monodelphis domestica. Our results are consistent with those from other species in that the piRNA-like candidate sequences range in size from 28 to 31 nucleotides, show a pronounced preference for uridine at the 5' end, are transcribed from a few large clusters, appear to target transposons, and display virtually no sequence conservation.

Keywords
  • Animals,
  • Base Sequence,
  • Clone Cells,
  • DNA Transposable Elements/genetics,
  • Male,
  • Molecular Sequence Data,
  • Monodelphis/genetics,
  • Multigene Family,
  • RNA,
  • Small Interfering/genetics,
  • Software,
  • Transcription,
  • Genetic
Published Article/Book Citation
Mammalian genome, 19:7-8 (2008) pp.581-586.
Citation Information
Eric J. Devor, L. Huang and P. B. Samollow. "PiRNA-like RNAs in the marsupial Monodelphis domestica identify transcription clusters and likely marsupial transposon targets" Mammalian genome Vol. 19 Iss. 7-8 (2008) p. 581 - 586 ISSN: 0938-8990
Available at: http://works.bepress.com/eric_devor/40/