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Article
H19/miR-675 non-coding RNA expression differentiates among cancers of the human endometrium.
Proceedings in Obstetrics and Gynecology
  • Eric J Devor, University of Iowa
  • Jill N. DeMik, University of Iowa
  • Brandon M. Schickling, University of Iowa
  • Michael J. Goodheart, University of Iowa
  • Kimberly K. Leslie, University of Iowa
Peer Reviewed
0
Publication Date
7-28-2011
Abstract
H19 is a maternally expressed non-coding RNA located at chromosome 11p15.5 near the reciprocally imprinted insulin-like growth factor 2 (IGF2) gene. Though the function of H19 is unknown, it is transcribed during embryonic development after which transcription is absent in all but a few tissues including cardiac muscle, breast, ovary, uterus, and placenta. Linking H19, miR-675 and RB1 expression with serous tumors of the endometrium suggests that RB1 suppression may be a differentiating event in serous tumorigenesis.
Keywords
  • endometrium,
  • endometrial cancer,
  • RNA
Total Pages
1
Financial Disclosure
This work supported in part by NIH 2CA99908-7 and the Department of Obstetrics and Gynecology Research and Development Fund.
Rights
Copyright © Eric J. Devor, Jill N. DeMik, Brandon M. Schickling, Michael J. Goodheart, and Kimberly K. Leslie, 2011.
Creative Commons License
Creative Commons Attribution 3.0
Citation Information
Eric J Devor, Jill N. DeMik, Brandon M. Schickling, Michael J. Goodheart, et al.. "H19/miR-675 non-coding RNA expression differentiates among cancers of the human endometrium." (2011) p. 1 - 1 ISSN: 2154-4751
Available at: http://works.bepress.com/eric_devor/4/