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Article
MicroRNAs, Cellular Behavior, and Endometrial Cancer
Proceedings in Obstetrics and Gynecology
  • Eric J Devor, University of Iowa
Peer Reviewed
0
Publication Date
10-1-2010
Abstract

Endometrial cancer is the most common gynecological cancer and the fourth most common cancer in women worldwide. In spite of its’ relative importance to overall morbidity among women, molecular research in endometrial cancers lags far behind other cancers such as breast and colorectal. Nowhere is this more true than in research in the newly emergent field of post-transcriptional gene regulation by small, regulatory RNAs, primarily microRNAs (miRNAs). Here, structure, biogenesis, and mode of action of miRNAs is presented along with a brief overview of the role of miRNAs in carcinogenesis and a review of the few miRNA studies in endometrial cancer carried out to date.

Keywords
  • microRNA,
  • cancer,
  • cellular behavior,
  • dysregulation,
  • endometrial cancer
Total Pages
15
Financial Disclosure
The authors report no conflict of interest.
Rights
Copyright © The University of Iowa, 2010.
Creative Commons License
Creative Commons Attribution 3.0
Citation Information
Devor EJ. MicroRNAs, Cellular Behavior, and Endometrial Cancer. Proc Obstet Gynecol. 2010 Oct;1(2):Article 1[15 p.]. Available from: http://ir.uiowa.edu/pog/vol1/iss2/1/. Free full text article.