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Article
Marsupial-specific microRNAs evolved from marsupial-specific transposable elements
Gene
  • Eric J. Devor, University of Iowa
  • A. S. Peek
  • W. Lanier
  • P. B. Samollow
Document Type
Article
Peer Reviewed
1
Publication Date
12-15-2009
NLM Title Abbreviation
Gene
PubMed ID
19577616
DOI of Published Version
10.1016/j.gene.2009.06.019
Abstract
Using a direct miRNA cloning strategy we previously identified fourteen marsupial- or species-specific microRNAs in the marsupial species Monodelphis domestica. In the present study we examined each of the pre-miRNAs and their flanking sequences and demonstrate that half of these miRNAs evolved from marsupial-specific transposable elements. These findings reinforce the view that transposable elements are a previously unappreciated source of new, lineage-specific microRNAs.
Keywords
  • Animals,
  • Base Sequence,
  • DNA Transposable Elements/genetics/physiology,
  • Evolution,
  • Molecular,
  • Genetic Variation/physiology,
  • Male,
  • Marsupialia/genetics,
  • MicroRNAs/genetics,
  • Molecular Sequence Data,
  • Nucleic Acid Conformation,
  • Phylogeny,
  • Sequence Homology,
  • Nucleic Acid,
  • Species Specificity
Published Article/Book Citation
Gene, 448:2 (2009) pp.187-191.
Citation Information
Eric J. Devor, A. S. Peek, W. Lanier and P. B. Samollow. "Marsupial-specific microRNAs evolved from marsupial-specific transposable elements" Gene Vol. 448 Iss. 2 (2009) p. 187 - 191 ISSN: 1879-0038
Available at: http://works.bepress.com/eric_devor/108/