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Article
Method for solid state genome analysis
Genetics, Development and Cell Biology Patents
  • Eric Henderson, Iowa State University
  • Michael P. Lynch
Document Type
Patent
Publication Date
4-6-2004
Abstract

The invention is a solid state process for analyzing genomes by visualizing sequence specific markers (e.g., proteins that bind a defined DNA sequence elements) by scanning probe microscopy. The method includes linear display of the nucleic acid on a solid surface, image acquisition by the scanning probe microscope, and digital data analysis. The acts of the method result in a bar code type display of each fragment of the DNA sample. These bar codes are then used to place the fragments in the order they appear on the original DNA sample.

Patent Number
US 6,716,578 B1
Assignee
BioForce Nanosciences, Inc.
Application Number
09/519,271
Date Filed
3-7-2000
Language
en
File Format
application/pdf
Citation Information
Eric Henderson and Michael P. Lynch. "Method for solid state genome analysis" (2004)
Available at: http://works.bepress.com/eric-henderson/49/