Other
Evaluating binding affinities by force stratification and force panning
Genetics, Development and Cell Biology Patents
Document Type
Patent
Publication Date
6-13-2006
Disciplines
Abstract
The present invention is a method for selectively removing objects from a surface utilizing a probe. The probe is scanned over the surface utilizing a greater and greater relative amount of force so that a certain number of the objects are removed from the surface. The force required to remove the objects from the surface can be calculated utilizing Hook's law and the spring constant of the probe. After removal of the objects that have a relatively weaker binding affinity with the surface, the remaining objects can be harvested, characterized, and subjected to further study.
Patent Number
US 7,060,448 B2
Assignee
BioForce Nanosciences, Inc.
Application Number
10/958,092
Date Filed
10-4-2004
Language
en
File Format
application/pdf
Citation Information
Eric Henderson and Curtis Mosher. "Evaluating binding affinities by force stratification and force panning" (2006) Available at: http://works.bepress.com/eric-henderson/47/