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Article
An overhanging 3' terminus is a conserved feature of telomeres
Molecular and Cellular Biology
  • Eric R. Henderson, Iowa State University
  • Elizabeth H. Blackburn, University of California - Berkeley
Document Type
Article
Publication Version
Published Version
Publication Date
1-1-1989
DOI
10.1128/MCB.9.1.345
Abstract

The reactivity of single-stranded thymidines with osmium tetraoxide was used to demonstrate the existence of a terminal overhang of the G-rich strand of telomeres from two distantly related eucaryotes, the ciliated protozoan Tetrahymena spp. and the acellular slime mold Didymium spp. Conservation of a G-strand overhang at the molecular terminus of telomeres is consistent with our suggestion that an unusual DNA structure formed by the G-strand overhang is important for telomere function (E. Henderson, C. C. Hardin, S. K. Wolk, I. Tinoco Jr., and E. H. Blackburn, Cell 51:899-908, 1987).

Comments

This article is from Molecular and Cellular Biology 9 (1989): 345, doi: 10.1128/MCB.9.1.345. Posted with permission.

Copyright Owner
American Society for Microbiology
Language
en
File Format
application/pdf
Citation Information
Eric R. Henderson and Elizabeth H. Blackburn. "An overhanging 3' terminus is a conserved feature of telomeres" Molecular and Cellular Biology Vol. 9 Iss. 1 (1989) p. 345 - 348
Available at: http://works.bepress.com/eric-henderson/12/