An overhanging 3' terminus is a conserved feature of telomeresMolecular and Cellular Biology
Publication VersionPublished Version
AbstractThe reactivity of single-stranded thymidines with osmium tetraoxide was used to demonstrate the existence of a terminal overhang of the G-rich strand of telomeres from two distantly related eucaryotes, the ciliated protozoan Tetrahymena spp. and the acellular slime mold Didymium spp. Conservation of a G-strand overhang at the molecular terminus of telomeres is consistent with our suggestion that an unusual DNA structure formed by the G-strand overhang is important for telomere function (E. Henderson, C. C. Hardin, S. K. Wolk, I. Tinoco Jr., and E. H. Blackburn, Cell 51:899-908, 1987).
Copyright OwnerAmerican Society for Microbiology
Citation InformationEric R. Henderson and Elizabeth H. Blackburn. "An overhanging 3' terminus is a conserved feature of telomeres" Molecular and Cellular Biology Vol. 9 Iss. 1 (1989) p. 345 - 348
Available at: http://works.bepress.com/eric-henderson/12/