Article
Stimulation of defective Gunn-rat Liver Uridine diphosphate Glucuronyltransferase activity in vitro by Alkyl ketones
Biochemical Journal
Publication Date
3-1-1979
Document Type
Article
Disciplines
Abstract
Addition of alkyl ketone (10mM) to Gunn-rat liver homogenates increased UDP-glucuronyltransferase activity towards 2-aminophenol by 10--20 fold, up to enhanced values of enzyme activity observed with similarly treated Wistar-rat liver homogenates. Alkyl ketones also activate the defective enzyme purified from Gunn-rat liver. This genetic deficiency of UDP-glucuronyltransferase activity is no longer apparent when assayed in the presence of alkyl ketones.
Citation Information
El-Nasir Lalani and Burchell B. "Stimulation of defective Gunn-rat Liver Uridine diphosphate Glucuronyltransferase activity in vitro by Alkyl ketones" Biochemical Journal Vol. 177 Iss. 3 (1979) p. 993 - 995 Available at: http://works.bepress.com/elnasir_lalani/74/