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Article
Quantification of penicillin G and procaine in equine urine and plasma using high performance liquid chromatography
Journal of Chromatography B: Biomedical Sciences and Applications (1998)
  • Y. Luo
  • Elizabeth McNamara (Brown), Binghamton University--SUNY
  • M. Fennell
  • D. Teleis
  • L. May
  • J. Rudy
  • A. Watson
  • C. Uboh
  • L. Soma
Abstract
A rapid and sensitive method for the extraction and quantification of penicillin-G and procaine in horse urine and plasma samples has been successfully developed. The method involves the use of solid-phase extraction (SPE) for penicillin-G, liquid-liquid extraction (LLE) for procaine, and high-performance liquid chromatography (HPLC) for the quantification of penicillin-G and procaine. The new method described here has been successfully applied in the pharmacokinetic studies of procaine, penicillin-G and procaine-penicillin-G administrations in the horse.
Keywords
  • Penicillin G/blood,
  • Chromatography,
  • High Pressure Liquid/methods*
Disciplines
Publication Date
1998
Citation Information
Y. Luo, Elizabeth McNamara (Brown), M. Fennell, D. Teleis, et al.. "Quantification of penicillin G and procaine in equine urine and plasma using high performance liquid chromatography" Journal of Chromatography B: Biomedical Sciences and Applications Vol. 714 Iss. 2 (1998) p. 269 - 276
Available at: http://works.bepress.com/elizabeth-brown/7/