Skip to main content
NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies
Emergency Medicine Publications and Presentations
  • Gail D'Onofrio, Yale University School of Medicine
  • Edward C. Jauch, Medical University of South Carolina
  • Andrew Jagoda, Mount Sinai School of Medicine
  • Michael H. Allen, University of Colorado–Denver
  • Deidre Anglin, University of Southern California Keck School of Medicine
  • William G. Barsan, University of Michigan
  • Rachel P. Berger, University of Pittsburgh School of Medicine
  • Bentley J. Bobrow, Mayo Clinic College of Medicine
  • Edwin D. Boudreaux, University of Massachusetts Medical School
  • Cheryl Bushnell, Wake Forest University
  • Yu-Feng Chan, Mount Sinai School of Medicine
  • Glenn Currier, University of Rochester Medical Center
  • Susan Eggly, Wayne State University School of Medicine
  • Rebecca Ichord, University of Pennsylvania School of Medicine
  • Gregory L. Larkin, Yale University School of Medicine
  • Daniel Laskowitz, Duke University Medical Center
  • Robert W. Neumar, University of Pennsylvania School of Medicine
  • David E. Newman-Toker, Johns Hopkins University
  • James Quinn, Stanford University
  • Katherine Shear, Columbia University
  • Knox H. Todd, Albert Einstein College of Medicine
  • Douglas Zatzick, University of Washington School of Medicine
UMMS Affiliation
Department of Emergency Medicine
Publication Date
Document Type
Adolescent; Adult; Advisory Committees; *Biomedical Research; Brain Injuries; Child; Emergencies; *Emergency Medical Services; Female; Humans; Mental Disorders; *National Institutes of Health (U.S.); Nervous System Diseases; Pregnancy; United States
STUDY OBJECTIVE: The Institute of Medicine Committee on the Future of Emergency Care in the United States Health System (2003) identified a need to enhance the research base for emergency care. As a result, a National Institutes of Health (NIH) Task Force on Research in Emergency Medicine was formed to enhance NIH support for emergency care research. Members of the NIH Task Force and academic leaders in emergency care participated in 3 Roundtable discussions to prioritize current opportunities for enhancing and conducting emergency care research. We identify key research questions essential to advancing the science of emergency care and discuss the barriers and strategies to advance research by exploring the collaboration between NIH and the emergency care community. METHODS: Experts from emergency medicine, neurology, psychiatry, and public health assembled to review critical areas in need of investigation, current gaps in knowledge, barriers, and opportunities. Neurologic emergencies included cerebral resuscitation, pain, stroke, syncope, traumatic brain injury, and pregnancy. Mental health topics included suicide, agitation and delirium, substances, posttraumatic stress, violence, and bereavement. RESULTS: Presentations and group discussion firmly established the need for translational research to bring basic science concepts into the clinical arena. A coordinated continuum of the health care system that ensures rapid identification and stabilization and extends through discharge is necessary to maximize overall patient outcomes. There is a paucity of well-designed, focused research on diagnostic testing, clinical decisionmaking, and treatments in the emergency setting. Barriers include the limited number of experienced researchers in emergency medicine, limited dedicated research funding, and difficulties of conducting research in chaotic emergency environments stressed by crowding and limited resources. Several themes emerged during the course of the roundtable discussion, including the need for development of (1) a research infrastructure for the rapid identification, consent, and tracking of research subjects that incorporates innovative informatics technologies, essential for future research; (2) diagnostic strategies and tools necessary to understand key populations and the process of medical decisionmaking, including the investigation of the pathobiology of symptoms and symptom-oriented therapies; (3) collaborative research networks to provide unique opportunities to form partnerships, leverage patient cohorts and clinical and financial resources, and share data; (4) formal research training programs integral for creating new knowledge and advancing the science and practice of emergency medicine; and (5) recognition that emergency care is part of an integrated system from emergency medical services dispatch to discharge. The NIH Roundtable "Opportunities to Advance Research on Neurological and Psychiatric Emergencies" created a framework to guide future emergency medicine-based research initiatives. CONCLUSION: Emergency departments provide the portal of access to the health care system for most patients with acute neurologic and psychiatric illness. Emergency physicians and colleagues are primed to investigate neurologic and psychiatric emergencies that will directly improve the delivery of care and patient outcomes.
DOI of Published Version
Ann Emerg Med. 2010 Nov;56(5):551-64. Link to article on publisher's site
Related Resources
Link to Article in PubMed
PubMed ID
Citation Information
Gail D'Onofrio, Edward C. Jauch, Andrew Jagoda, Michael H. Allen, et al.. "NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies" Vol. 56 Iss. 5 (2010) ISSN: 0196-0644 (Linking)
Available at: