Article
Contralateral Breast Cancer With Multiple Primary Neoplasms in a Patient With Neurofibromatosis Type 1: A Case Report and Review of the Literature
Cureus
(2021)
Abstract
Neurofibromatosis type 1 (NF1) is an autosomal dominant neuroectodermal disorder associated with
increased risk for several neural and non-neural malignancies. The link between NF1 and breast cancer has
recently been established, with patients with NF1 being at higher risk for developing breast cancer, more
likely to get breast cancer at a younger age, and more likely to have their breast cancer present with more
adverse prognostic factors. Although rare, several cases of NF1 patients with contralateral breast cancer
have been mentioned in the literature. We report the case of one such patient who developed contralateral
breast cancer 40 years after her initial breast cancer diagnosis.
Keywords
- oncology,
- radiation oncology,
- medical oncology,
- breast cancer,
- neurofibromatosis type 1
Disciplines
Publication Date
Spring March 6, 2021
DOI
10.7759/cureus.13738
Publisher Statement
open access
Citation Information
Shifaz Veettil, Jawaid Younus and Edward Yu. "Contralateral Breast Cancer With Multiple Primary Neoplasms in a Patient With Neurofibromatosis Type 1: A Case Report and Review of the Literature" Cureus Vol. 13 Iss. 3 (2021) p. e13738 Available at: http://works.bepress.com/edwardyu/118/