Lung cancer is the major cause of cancer – related mortality in men and women world wide. In the last three decades the management of lung cancer has changed and the mortality of this disease has improved. This is partly due to rapid progress in the research, diagnosis, and treatment of lung cancer. The present Special Hot Topic Series entitled “Lung Cancer - What Is New? “reviews the progress of management of thoracic cancer. This work is the result of diligent efforts of many investigators, authors, reviewers and support personnel who we are indebted to for their perseverance. This special series on lung cancer is dedicated to my aunt Jade, and to all patients who have battled, or are battling this disease.