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Nanorods Formed from a New Class of Peptidomimetics
Macromolecules
  • Youhong Niu, University of South Florida
  • Haifan Wu, University of South Florida
  • Rongfu Huang, University of South Florida
  • Qiao Qiao, University of South Florida
  • Frankie Costanza, University of South Florida
  • Xi-Sen Wang, University of South Florida
  • Yaogang Hu, University of South Florida
  • Mohamad Nassir Amin, University of South Florida
  • Anh-My Nguyen, University of South Florida
  • James Zhang, University of South Florida
  • Edward M Haller, University of South Florida
  • Shengqian Ma, University of South Florida
  • Xiao Li, University of South Florida
  • Jianfeng Cai, University of South Florida
Document Type
Article
Publication Date
9-7-2012
Digital Object Identifier (DOI)
https://doi.org/10.1021/ma3015992
Abstract

Although peptide amphiphiles have been explored as nanomaterials for different applications, nanostructures formed by hierarchical molecular assembly of sequence-specific peptidomimetics are much less developed. Such protein-like nanomaterials could enhance the current application of peptide-based amphiphiles by enriching the diversity of nanostructures, increasing in vivostability for biomedical applications, and facilitating the understanding of biomacromolecular self-assembly. Herein we present a biomimetic γ-AApeptide amphiphile which forms nanorods. Our results demonstrate the capability of γ-AApeptide amphiphiles as a potential scaffold for the preparation of biomimetic and bioinspired nanostructures. The programmability and biocompatibility of γ-AApeptides could lead to novel nanomaterials for a wide variety of applications.

Citation / Publisher Attribution

Macromolecules, v. 45, issue 18, p. 7350–7355

Citation Information
Youhong Niu, Haifan Wu, Rongfu Huang, Qiao Qiao, et al.. "Nanorods Formed from a New Class of Peptidomimetics" Macromolecules Vol. 45 Iss. 18 (2012) p. 7350 - 7355
Available at: http://works.bepress.com/edward_haller/31/