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Article
Electrofusion of Individual Animal Cells Directly to Intact Corneal Epithelial Tissue
Biochimica et Biophysica Acta (BBA) - Biomembranes
  • Robert J Grasso, University of South Florida
  • Richard Heller, University of South Florida
  • John C Cooley, University of South Florida
  • Edward M Haller, University of South Florida
Document Type
Article
Publication Date
3-27-1989
Keywords
  • Electrofusion,
  • Cell hybrid,
  • Membrane receptor transfer,
  • (Human cell),
  • (Rabbit tissue),
  • (Somatic cell hybrid)
Digital Object Identifier (DOI)
https://doi.org/10.1016/0005-2736(89)90193-4
Abstract

An electromechanical process was developed to electrofuse human and nonhuman cultured cells directly to rabbit corneal epithelial tissue in vitro and in situ. This new process was utilized successfully to incorporate functional gonococcal membrane attachment receptors from human lymphoma cells into superficial rabbit corneal epithelium. Thus, cell-tissue electrofusion biotechnology may be employed to establish unique and novel animal models for investigating receptor-mediated processes in vivo.

Citation / Publisher Attribution

Biochimica et Biophysica Acta (BBA) - Biomembranes, v. 980, issue 1, p. 9-14

Citation Information
Robert J Grasso, Richard Heller, John C Cooley and Edward M Haller. "Electrofusion of Individual Animal Cells Directly to Intact Corneal Epithelial Tissue" Biochimica et Biophysica Acta (BBA) - Biomembranes Vol. 980 Iss. 1 (1989) p. 9 - 14
Available at: http://works.bepress.com/edward_haller/26/