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Article
Computational Analysis of Hybrid Norwood Circulation with Distal Aortic Arch Obstruction and Reverse Blalock-Taussig Shunt
Annals of Thoracic Surgery
  • Andres Ceballos, University of Central Florida
  • I. Ricardo Argueta-Morales, Arnold Palmer Hospital for Children
  • Eduardo Divo, Embry-Riddle Aeronautical University
  • Ruben Osorio, University of Central Florida
  • Christopher A. Caldarone
  • Alain J. Kassab, University of Central Florida
  • William M. DeCampli, University of Central Florida
Document Type
Article
Publication/Presentation Date
1-1-2012
Abstract/Description
BACKGROUND: The hemodynamics characteristics of the hybrid Norwood (HN) procedure differ from those of the conventional Norwood and are not fully understood. We present a multi-scale model of HN circulation to understand local hemodynamics and effects of aortic arch stenosis and a reverse Blalock-Taussig shunt (RBTS) on coronary and carotid perfusion. METHODS: Four 3-dimensional models of four HN anatomic variants were developed, with and without 90% distal preductal arch stenosis and with and without a 4-mm RBTS. A lumped parameter model of the circulation was coupled to a local 3-dimensional computational fluid dynamics model. Outputs from the lumped parameter model provided waveform boundary conditions for the computational fluid dynamics model. RESULTS: A 90% distal arch stenosis reduced pressure and net flow-rate through the coronary and carotid arteries by 30%. Addition of the RBTS completely restored pressure and flow rate to baseline in these vessels. Zones of flow stagnation, flow reversal, and recirculation in the presence of stenosis were rendered more orderly by addition of the RBTS. In the absence of stenosis, presence of the shunt resulted in extensive zones of disturbed flow within the RBTS and arch. CONCLUSIONS: We found that a 4-mm × 21-mm RBTS completely compensated for the effects of a 90% discrete stenosis of the distal aortic arch in the HN. Placed preventatively, the RBTS and arch displayed zones with thrombogenic potential showing recirculation and stagnation that persist for a substantial fraction of the cardiac cycle, indicating that anticoagulation should be considered with a prophylactic RBTS.
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Citation Information
Andres Ceballos, I. Ricardo Argueta-Morales, Eduardo Divo, Ruben Osorio, et al.. "Computational Analysis of Hybrid Norwood Circulation with Distal Aortic Arch Obstruction and Reverse Blalock-Taussig Shunt" Annals of Thoracic Surgery Vol. 94 Iss. 5 (2012) p. 1540 - 1550
Available at: http://works.bepress.com/eduardo_divo/10/