A new medium-sized species of leptodactylid frog, genus Phrynopus is described from the eastern Andean slopes of central Peru (Departamento de Huanuco, Cordillera de Carpish, 2960m above sea level). The new species differs from all described species of the genus by having long and slim extremities, dorsum and ventrum dark grey, throat with a large yellowish mustard blotch, each side of midventer with a large yellowish mustard rectangular blotch, and toes and fingers partly creamy yellow. The new species is documented by a single female specimen which did not show saltatory locomotion. In the Cordillera de Carpish, the new species occurs sympatrically with Bufo chavin, Eleutherodactylus sp., Cochranella sp., Phrynopus kauneorum and Phrynopus dagmarae.