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Dr. Ronald Bartzatt
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University of Nebraska at Omaha
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Department of Chemistry
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Research Works
Research Works
(18)
Article
Prediction of Novel Anti-Ebola Virus Compounds Utilizing Artificial Neural Network ...
World Journal of Pharmaceutical Research (2018)
Ronald Bartzatt
Artificial Neural Network (ANN) analysis is shown to predict the molecular properties of new anti-EBOLA compounds following training/learning by use ...
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Article
Neurological Impact of Zinc Excess and Deficiency In vivo
European Journal of Nutrition & Food Safety (ISSN: 2347-5641) (2017)
Ronald Bartzatt
Zinc is an essential mineral that can cause pathological effects whether in excess or deficiency. Zinc is a component for ...
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Article
Pyrimethamine Based Anti-protozoan Agents from Isostere and Heuristic Structure-similarity Search
British Journal of Pharmaceutical Research (2017)
Ronald Bartzatt
Aims: To generate new medicaments for control and treatment of the parasitic protozoan Toxoplasma gondii. Study Design: Structure similarity search ...
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Article
Comparative Analysis of Antihistamines and Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Properties ...
Journal of Advances in Medical and Pharmaceutical Sciences (ISSN: 2394-1111) (2017)
Ronald Bartzatt
Aims: To determine the molecular properties of common antihistamines and non-steroidal antiinflammatory agents (NSAIDs). To identify interrelationships among these two ...
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Article
Relative Properties and Relative Potency of Various Hydrazide Compounds That ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) (2017)
Ronald Bartzatt
The molecular properties of compounds expressing growth inhibition of Mycobacterium tuberculosis are determined and examined for underlying relationships by pattern ...
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Article
Potency and Properties of Hydrazide Compounds That Inhibit the Growth ...
Journal of Advances in Medical and Pharmaceutical Sciences (2016)
Ronald Bartzatt
Aims: To examine the properties of hydrazide compounds shown to inhibit Mycobacterium tuberculosis. To identify properties that affect efficiency of ...
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Article
Acridine orange staining of virus infected host cells to monitor ...
Analytical Chemistry: An Indian Journal (2016)
Ronald Bartzatt
Acridine orange staining is a methodology for nucleic acid selective metachromatic staining that is useful for following cell cycle determination. ...
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Article
Four Compounds Suppressing Growth of Mycobacterium tuberculosis
Journal of Advances in Medical and Pharmaceutical Sciences (2016)
Ronald Bartzatt, Preeti Sule, Woojung Kim and Jeffrey D. Cirillo
Aims: To demonstrate the efficacy of several small molecular weight compounds having hydrazide groups, for inhibiting the growth of Mycobacterium ...
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Article
Properties and Drug-likeness of Compounds That Inhibit Ebola Virus Disease ...
International Journal of TROPICAL DISEASE & Health (2016)
Ronald Bartzatt
Aims: To present the molecular structures of compounds that has been shown to inhibit the proliferation of Ebola virus. To ...
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Article
Design of COX-1 Inhibitors Utilizing Class I Isosteres, Class II ...
Journal of Advances in Medical and Pharmaceutical Sciences (2015)
Ronald Bartzatt
Aims: To identify isosteres and bioisosteres suitable for substitution on the molecular scaffold of meclofenamic acid and tolfenamic acid. The ...
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Article
Measuring the Alkylation Kinetics and Drug Likeness of Four Candidate ...
Archives of Current Research International (2015)
Ronald Bartzatt
Aims: To synthesize small molecule alkylating compounds and analyze the kinetics of the alkylation in aqueous solution. Determine molecular properties ...
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Article
Potential Antineoplastic Structural Variations of Uracil Mustard (Uramustine) Retaining Cytotoxic ...
Journal of Cancer and Tumor International (2015)
Ronald Bartzatt
Aims: To present 12 new variants of uracil mustard having drug-like properties and cytotoxic functional group, by utilizing uracil mustard ...
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Article
Novel Tuberculostatic Agents Suitable for Treatment of Mycobacterium tuberculosis Infections ...
British Journal of Pharmaceutical Research (2014)
Ronald Bartzatt, Preeti Sule, Suat L.G. Cirillo and Jeffrey D. Cirillo
Aims: To demonstrate the efficacy of five small molecule compounds for inhibiting the growth of Mycobacterium tuberculosis. To present evidence ...
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Article
Lomustine Analogous Drug Structures for Intervention of Brain and Spinal ...
Chemotherapy Research and Practice (2013)
Ronald Bartzatt
Lomustine is a nitrosourea anticancer agent shown to be effective for treatment of childhood medulloblastoma. In silico substructure searches produced ...
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Article
Spectrophotometric and colorimetic methodology to detect and quantify hydrazide based ...
Environmental Science: An Indian Journal (2010)
Ronald Bartzatt
Pharmaceuticals having the hydrazide functional group are an important division within anti-tuberculosis, anti-parasitic, anti-cancer, and anti-radiation chemotherapeutics. This work presents ...
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Article
Evaluation of a Simple Carrier Molecule to Enhance Drug Penetration ...
Physiological Chemistry and Physics and Medical NMR (2004)
Ronald Bartzatt
Nicotinic acid is shown to be comparable to dihydropyridine in its capacity to facilitate penetration of an attached antibacterial drug ...
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Article
Utilizing Structure Property Correlations to Predict and Analyze Two Derivatives ...
Journal of Undergraduate Chemistry Research (2003)
C. Malesa, J. Stoddard and Ronald Bartzatt
Structure Property Correlation methods such as regression analysis and pattern recognition are applied to predict the molecular properties of two ...
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Article
Expression of Epstein-Barr virus (EBV) DNA and cloned DNA fragments ...
Chemistry Faculty Proceedings & Presentations (1984)
David J. Volsky, Thomas Gross, Faruk Sinangil, Charles Kuszynski, et al.
Purified EBV DNA and cloned DNA fragments were trapped in Sendai virus (SV) envelopes during envelope reconstitution. The DNA-loaded reconstituted ...
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