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Cerebral and Choroidal Metastases with Retinal detachement, Secondary to Rectal Cancer: A case report
World Journal of Colorectal Surgery (2010)
  • Dr. John Marks, Lankenau Medical Center
  • Dr. Elsa Valsdottir, Lankenau Medical Center
  • Dr. Eric Zeger, Lankenau Medical Center
  • Dr. Carol Shields

Colorectal cancer is the most common abdominal visceral cancer diagnosed in men and in women annually and is estimated that about 106,100 new case of colon cancer and 40, 870 cases of rectal cancer would be diagnosed in 2009.

Metastasis secondary to colorectal cancer will occur in 10-20% of patients The most common metastatic sites of colorectal cancer include, liver metastases and pulmonary metastases. Metastatic brain tumors from colorectal cancer are relatively rare between 1.03 and 1.8%.

Brain metastases in colorectal cancers are rarely encountered. Although not statistically significant, concurrent cerebral and pulmonary metastases were associated with lower rectal tumours when compared to either colonic or upper rectum. Only 4% of gastrointestinal cancers metastasize to the uvea with choroidal metastasis from colon and rectal cancer being exceedingly rare as they commonly metastasize by way of the portal route.

Treatment approaches must take into account the palliative nature of care in these patients, focusing on maintaining vision in conjunction with quality of life. The presence,of these forms of metastasis, should be considered in the differential diagnoses when a patient with a history of colorectal cancer presents with neurological deficits. However, if a patient presents with a primary finding of choroidal metastasis with or without retinal detachment gastrointestinal tract malignancies, specifically colorectal cancer, should be considered as a the potential primary site of origin.

  • Brain,
  • Rectal Metastases,
  • Retinal detachment
Publication Date
Citation Information
Dr. John Marks, Dr. Elsa Valsdottir, Dr. Eric Zeger and Dr. Carol Shields. "Cerebral and Choroidal Metastases with Retinal detachement, Secondary to Rectal Cancer: A case report" World Journal of Colorectal Surgery Vol. 2 Iss. 1 (2010)
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