Dr. Amarie’s research builds on and expands his previous work on novel optical micro-biosensors for real-time dynamic quantification of biomolecular interactions and microfluidics devices for quantitative control of reagent delivery, stimulation and measurement of single-cell behaviors. He plans to employ these devices and related tools in experiments that in the long run will address the basic biophysical principles that control the formation and dynamics of normal and diseased tissues. He is interested in exploring the mechanisms governing the formation of stationary surface plasmon modes in micro-cavities resonators and quantify their dependence on materials parameters. Implementation of micro-biosensors into microfluidic devices will allow him to study cellular response under controlled chemical gradients and quantify protein concentrations outside cells at single-cell. Dr. Amarie’s research is interdisciplinary; spanning physics, biophysics, microfluidics, microscopy, biosensors, and chemical physics. He published ten peer-reviewed scientific articles, gave over twenty lectures and presentations and was awarded six patents of invention, with two more patent applications pending. He led the writing of nine grant proposals and collaborated on other eight, resulting in more than $1.2M in funding.