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Contribution to Book
Possible Role of the Transcription Factor Oct-3/4 in Control of Human Chorionic Gonadotropin Expression
Embryo Implantation
  • Limin Liu
  • Douglas W. Leaman, Wright State University - Main Campus
  • R. Michael Roberts
Document Type
Book Chapter
Publication Date
1-1-1999
Abstract

During a study on the regulation of interferon-i genes in choriocarcinoma cells, an hCGa-CAT construct was included as an internal control to check transfection efficiencies. Although Oct-3/4 coexpression had little effect on expression from an IFN-ti promoter that carried several potential Oct binding sequences, the hCGa-CAT construct was strongly silenced. This serendipitous discovery led to the data reported in this chapter and two earlier papers (1,2).

DOI
10.1007/978-1-4612-1548-6_22
Citation Information
Limin Liu, Douglas W. Leaman and R. Michael Roberts. "Possible Role of the Transcription Factor Oct-3/4 in Control of Human Chorionic Gonadotropin Expression" Embryo Implantation (1999) p. 261 - 270 ISSN: 978-1-4612-1548-6
Available at: http://works.bepress.com/douglas-leaman/52/