- Administration, Cutaneous,
- Cross-Over Studies,
- Diabetes Mellitus, Type 2,
- Diabetic Foot,
- Double-Blind Method,
- Middle Aged,
- Plant Extracts,
- Treatment Outcome,
- Wound Healing
OBJECTIVE: There is a medical need to evaluate new treatments that may improve wound healing. This study aimed to determine if Original Healing Salve (OHS, Puremedy, Inc.) a topical, botanically-enriched salve (BES), changes distal leg tissue oxygenation in people with type 2 diabetes.
METHOD: A randomised, controlled, crossover, double-blinded clinical trial comparing changes in cutaneous oxygen delivery (mean TcPO
RESULTS: A total of 16 participants were recruited. Analysis of the primary outcome demonstrated no statistically significant difference in TcPO
CONCLUSION: These findings support consideration of topical treatments containing botanical ingredients to increase cutaneous oxygen delivery in the lower extremity in patients with type 2 diabetes.
Available at: http://works.bepress.com/douglas-hanes/68/