The objective of this paper was to evaluate the deterioration of Portland Cement Concrete (PCC) slabs throughout trafficking. A full-scale accelerated pavement testing at the National Airport Pavement Test Facility (NAPTF) was conducted on Construction Cycle 6 (CC6) on rigid pavements with low, medium and high flexural strengths on both a concrete and asphalt stabilised base. Heavy Weight Deflectometer (HWD) testing was conducted on the test sections to backcalculate the stiffness of the layers. The majority of PCC deterioration occurred roughly within the first 1500–2000 passes of trafficking. On average, the MRS-1 (low flexural strength) PCC elastic modulus was found to decrease by 20%, from 5.0–.4 × 106 (34.5–37.2 GPa) to 4.0–4.3 × 106 psi (27.6–29.7 GPa), whereas the PCC elastic modulus of MRS-2 and MRS-3 was found to decrease by 17% and 22%, respectively. However, neither the MRS-2 nor MRS-3 elastic modulus was found to drop below 5.0 × 106 psi (34.5 GPa) after 15,000 passes.