The rationale for this case study was to describe the day-to-day experiences of living with chronic hepatitis C (CHC), as described by someone who relapsed after treatment. An evolving model of treatment experiences and symbolic interaction were used as conceptual underpinnings for this case study. Participant observation in community support groups and three in depth interviews with one individual held across 2 months took place in a naturalistic setting of the participant’s choice. Analysis of the participant interviews emphasized (1) the stigma of living with a reportable disease, its etiology, and the attitudes f an uninformed public, and (2) the trajectory of a relapser. Implications for practitioners must include an emphasis on the psychological and social impact of CHC. Comparison of this chronic illness trajectory to an existing model will assist in theory development.